1. Product and Company Information 2. Composition

TM
Material Safety Data Sheet
GX Buffer 2
1. Product and Company Information
Product name: Buffer 2
Common name: Not applicable
Compound name: Not applicable
Cepheid part numbers: 900-0128; 900-0121
Applied Biosystems part numbers: 4350025; 4350024
Company:
Cepheid
904 Caribbean Drive
Sunnyvale, CA 94089
USA
Emergency Tel. No: 1-888-838-3222 (Technical Support)
Manufactured for Applied Biosystems by American Biological Technologies, Inc.
Distributed by Cepheid.
2. Composition/Information on Ingredients
This product is a proprietary mixture composed of 99.7% water.
Product contains sodium azide at a concentration below threshold amounts for reporting
according to US OSHA hazard communication regulations (1%), but at a concentration that
should be considered for disposal and other environmental considerations.
3. Hazard Identification
Emergency Overview
This material does not meet the definition of a hazardous material as defined by US Federal
OSHA, 29 Code of Federal Regulations, 1910.1200, Hazard Communication Standard
POTENTIAL HEALTH EFFECTS:
Skin contact: Prolonged but constant contact with liquid may cause a reversible mild irritation
and dermatitis.
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Material Safety Data Sheet
GX Buffer 2
Eye contact: Prolonged but constant contact with liquid may cause reversible eye irritation
resulting in redness and watering.
Inhalation: Inhalation should not present a significant hazard as hazardous ingredients are not
present at concentrations > 1%. .
Ingestion: Excessive ingestion of liquid form can cause gastric distress and mild diarrhea.
Medical Conditions Aggravated By Exposure: None known or reported.
Target Organs: Not considered to affect target organs as not considered hazardous under US
OSHA regulation.
4. First Aid Measures/Routes of Entry
Skin contact: Wash with soap and water. If an irritation develops, contact medical personnel.
Eye contact: Immediately flush eyes with plenty of water. If an irritation develops, contact
medical personnel.
Inhalation: Remove to fresh air, seek medical attention if symptoms persist.
Ingestion: Drink a small amount of water. If symptoms develop, contact medical personnel.
5. Fire and Explosion Data
Flashpoint: Not applicable
Upper and Lower flammable limits: Not applicable
Flammable classification: Not applicable
General fire hazard information: Not applicable
Explosion hazards: Not applicable
Extinguishing media: Use extinguishing media appropriate for surrounding fire.
Fire fighting equipment: Firefighters should wear self-contained breathing apparatus for
surrounding fire with a full-face piece operated in the positive pressure demand mode when
fighting fires.
6. Accidental Release Measures
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Material Safety Data Sheet
GX Buffer 2
If material is released or spilled, cordon off spill area. Take proper precautions to minimize
exposure by using appropriate personal protective equipment (at a minimum an overgarment
such as a lab coat, and gloves). Soak up material with absorbent, e.g., paper towels or spill
pillows, and wash spill area thoroughly with soap and water. Dispose of collected material in
accordance with applicable waste disposal regulations.
7. Handling and Storage
Avoid contact with skin, eyes or clothing. Store in a cool and dry location.
8. Exposure Control/Personal Protection
Engineering Controls: Use in enclosed equipment as per kit directions.
Respiratory Protection: Not normally required. If the material is spilled or released, base the
choice of protection on the job activity and the potential for inhalation of mists.
Skin Protection: Protective (nitrile or rubber) gloves are recommended to minimize potential for
skin contact when handling. Wear long sleeves and other protective overgarment, such as a lab
coat. Base the choice of protection on the job activity and potential for skin contact.
Eye Protection: Wear safety glasses with side shields. If the material is spilled or released,
base the choice of protection on the job activity and potential for contact with eyes or face.
Other: Wash hands, face and other potentially exposed areas immediately after handling
material (especially before eating, drinking, or smoking). Decontaminate all protective
equipment after use.
9. Physical and Chemical Properties
Appearance: Clear liquid
Specific Gravity (Water = 1): Not available
Odor: None known
Evaporation Rate: Not available
Physical State: Liquid
Water/Oil Partition Coefficient: Not available
Boiling Point: Not available
Freezing point: Not available
Vapor Pressure: Not available
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Material Safety Data Sheet
GX Buffer 2
pH: 8.0
Density: Not available
Volatility: Not available
Solubility: Not available
Odor Threshold: Not available
10. Stability and Reactivity
Stability: Stable
Conditions to Avoid: Exposure to direct current electricity. Strong acids and bases can cause
rapid heating. Reaction with sodium metal can result in explosion.
Materials to Avoid: Incompatible with oxidizing materials, and may produce toxic fumes upon
decomposition.
Hazardous Polymerization: Will not occur.
11. Toxicological Information
LD50/LC50: Not available
Effects of Acute Overexposure: None known
Effects of Chronic Overexposure: None known
Sensitization of Material: None known
Carcinogenicity: None of the ingredients which are present at equal to or greater than 0.1% of
the product, are listed by OSHA, NTP, or IARC as suspect carcinogens.
Reproductive Toxicity: None reported
Teratogenicity: None reported
Mutagenicity: None reported
Toxicologically Synergistic Products: None reported
12. Ecological Information
Environmental Fate: No data for product.
Environmental Toxicity: No data for product. Product contains a low concentration (<0.1%) of
sodium azide, which is toxic to the environment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be flushed to sewer in compliance
with the facility permit and local regulation. If material becomes contaminated during use,
dispose of accordingly. Use appropriate methods based on federal and provincial statutes and
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Material Safety Data Sheet
GX Buffer 2
regulations and local by-laws. Contact local environmental agency for specific rules and
instruction.
14. Transport Information
The transport of this product is not regulated or restricted.
Proper DOT Shipping Name: Not applicable/ Not regulated
DOT Hazard Classification: Not applicable/Not regulated
15. Regulatory Information
California Proposition 65: This product does not contain chemicals known to the state of
California to cause cancer, birth defects, or other reproductive harm.
TSCA: All applicable chemicals in this product are listed under the TSCA chemical inventory.
SARA 302: Not Applicable. A small amount of sodium azide is present. The amount should be
well below the reportable quantity (1000 lbs) but should be taken into consideration in facilities
with multiple sources of azide.
SARA 313: Not Applicable. Sodium azide is below the de minimus concentration for SARA
313 reporting.
16. Other Information
The format of this Material Safety Data Sheet conforms to the requirements of US ANSI/CMA
guidelines.
Cepheid makes no warranties as to the accuracy or completeness of this information and
disclaims any liability in connection with its use. Cepheid’s obligations shall be only as set forth
in Cepheid’s standard terms and conditions of sale for this product. In no case will Cepheid be
liable for any incidental, indirect or consequential damages arising out of the sale, resale, use or
misuse of the product.
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