Annual Report 2009 - Český registr dárců krvetvorných buněk

Annual Report 2009 - Český registr dárců krvetvorných buněk

INSTITUT KLINICKÉ A EXPERIMENTÁLNÍ MEDICÍNY
VÍDEŇSKÁ 1958 / 9
ČESKÝ REGISTR DÁRCŮ KRVETVORNÝCH BUNĚK
140 21 PRAHA 4 – KRČ
AAnnnnuuaall RReeppoorrtt 22000099
Czech Stem Cells Registry (CSCR-Prague) former Czech Bone Marrow Donor Registry, was founded in
1991 in the Institute for Clinical and Experimental Medicine in Prague, Czech Republic. In the same
year, it became a member of the international network of unrelated bone marrow donor registries
which was managed from the coordinating centre in Leiden, Netherlands. CSCR is a member of
BMDW and WMDA.
CSCR gradually established contacts and joined other cooperating networks: National Marrow Donor
Program (NMDP) in Minneapolis, USA, in 1997 and European Marrow Donor Information System
(EMDIS) in Ulm, Germany.
CSCR searches in its database HLA matched donors both for Czech and international patients.
CSCR holds ISO 9001 certification dated September 2007.
FACTS/FIGURES :
I.
Number of donors :
At the end of December 2009, 23 332 donors were registered in CSCR.
Total number of registered donors as of
December 31, 2009
23 332
25 000
20 015
20 000
15 000
10 000
3317
5 000
0
Num ber of
stem cell
donors
Adresa:
Institut klinické a experimentální medicíny
Český registr dárců krvetvorných buněk – pavilon Z4
Vídeňská 1958/9
140 21 Praha 4
Num ber of
cord blood
units
Total num ber
of all donors
Tel.:26136 1011, 26136 2346
Fax: 26136 2370, 24171 2242
VÍDEŇSKÁ 1958 / 9
140 21 PRAHA 4 – KRČ
II.
INSTITUT KLINICKÉ A EXPERIMENTÁLNÍ MEDICÍNY
ČESKÝ REGISTR DÁRCŮ KRVETVORNÝCH BUNĚK
Number of donors/cord blood units newly added to the Registry during the year 2009 :
In 2009, CSCR added to database 1338 donors/CBUs.
Initial typing on donor samples was performed by serological methods in the HLA class I.
(A,B,C loci) and DNA methods were used for HLA class II. (DRB1*LR typing)
All CBUs entered in registry are ABDR*LR typed and units entered in year 2009 are
A, B,C,DRB1,DQB1 intermediate or HR typed.
Cord blood units are included in the CSCR registry pursuant to the agreement of CSCR and
the Cord Blood Bank of the Czech Republic.
III.
CSCR donors by gender and age :
CSCR donors by gender
10 053
9962
Male
Female
Adresa:
Institut klinické a experimentální medicíny
Český registr dárců krvetvorných buněk – pavilon Z4
Vídeňská 1958/9
140 21 Praha 4
Tel.:26136 1011, 26136 2346
Fax: 26136 2370, 24171 2242
INSTITUT KLINICKÉ A EXPERIMENTÁLNÍ MEDICÍNY
VÍDEŇSKÁ 1958 / 9
ČESKÝ REGISTR DÁRCŮ KRVETVORNÝCH BUNĚK
140 21 PRAHA 4 – KRČ
CSCR donors by age
5% 5%
18 - 25
18%
26 - 35
42%
36 - 45
46 - 55
55 and older
30%
IV.
Number of CSCR and international donors provided to Czech patients :
CSCR ran searches for 174 Czech patients last year.
74 transplants from unrelated donors found by CSCR were performed in cooperative
transplant centers in the Czech Republic.
Donations of PBSC created 2/3 donations in comparison with the bone marrow donations.
In four cases, cord blood unit was used for the transplant.
Transplants from unrelated donors in Czech Republic
60
48
50
40
BM Donors
c
30
PBSC Donors
22
CB Units
20
10
4
0
1
Adresa:
Institut klinické a experimentální medicíny
Český registr dárců krvetvorných buněk – pavilon Z4
Vídeňská 1958/9
140 21 Praha 4
Tel.:26136 1011, 26136 2346
Fax: 26136 2370, 24171 2242
INSTITUT KLINICKÉ A EXPERIMENTÁLNÍ MEDICÍNY
VÍDEŇSKÁ 1958 / 9
ČESKÝ REGISTR DÁRCŮ KRVETVORNÝCH BUNĚK
140 21 PRAHA 4 – KRČ
V.
Number of CSCR donors provided to international patients :
In 2009, a total number of 25 donations were provided for patients abroad.
For these transplants 2 bone marrow and 2 PBSC grafts were used.
The other 21 patients were transplanted with CBU.
Number of CSCR donors provided to international
patients
21
25
20
Bone Marrow
15
PBSC
CB Units
10
2
2
5
0
1
VI.
Number of donations from CSCR to patients in individual countries:
The highest number of Czech grafts was transplanted in France, then in the Netherlands
and in Great Britain.
Adresa:
Institut klinické a experimentální medicíny
Český registr dárců krvetvorných buněk – pavilon Z4
Vídeňská 1958/9
140 21 Praha 4
Tel.:26136 1011, 26136 2346
Fax: 26136 2370, 24171 2242